Sarcomatoid Mesothelioma: A Rare and Aggressive Cancer

Welcome to our informative article about sarcomatoid mesothelioma. This type of cancer is rare and aggressive, and we understand that it can be overwhelming to receive a diagnosis or learn about it for the first time. That’s why we’ve created this article to provide you with comprehensive and reliable information about sarcomatoid mesothelioma.

What Is Sarcomatoid Mesothelioma?

Mesothelioma is a type of cancer that develops in the lining of the body’s internal organs, particularly the lungs, heart, and abdomen. Sarcomatoid mesothelioma is a subtype that accounts for approximately 10-20% of all mesothelioma cases. It is a particularly aggressive form of the disease and is associated with a poor prognosis.

What Causes Sarcomatoid Mesothelioma?

Sarcomatoid mesothelioma is predominantly caused by exposure to asbestos, a naturally occurring mineral that was widely used in various industries, including construction, shipbuilding, and manufacturing. The microscopic fibers of asbestos can penetrate the lining of internal organs, causing inflammation, tissue scarring, and eventually, cancerous tumors to form.

What Are the Symptoms of Sarcomatoid Mesothelioma?

The symptoms of sarcomatoid mesothelioma may take decades to appear and can often be mistaken for other less severe conditions. Some of the most common symptoms of the disease include:

Common Symptoms Rare Symptoms
Difficulty breathing Loss of appetite
Chest pain Fever
Coughing Sweating
Fatigue Swelling in the face or arms
Weight loss Anemia

How Is Sarcomatoid Mesothelioma Diagnosed?

Diagnosing sarcomatoid mesothelioma can be challenging due to its rarity and similarity to other diseases. Your doctor may order several tests and procedures to confirm a diagnosis, including:

  • Imaging tests (e.g., X-rays, CT scans, MRIs)
  • Biopsy – a small tissue sample taken from the affected area to be examined under a microscope
  • Blood tests

Is There a Cure for Sarcomatoid Mesothelioma?

At present, there is no known cure for sarcomatoid mesothelioma, and treatment is mainly focused on managing symptoms and improving quality of life. Treatment options may include:

  • Surgery to remove the affected tissue
  • Chemotherapy – medication used to kill cancer cells
  • Radiation therapy – high-energy radiation used to shrink tumors and relieve symptoms

What Is the Prognosis for Sarcomatoid Mesothelioma?

The prognosis for sarcomatoid mesothelioma is generally poor due to its aggressive nature and tendency to spread rapidly. The five-year survival rate is estimated to be around 8%, but this can vary depending on several factors, including the stage of the disease, the patient’s age and overall health, and the type of treatment received.

FAQs About Sarcomatoid Mesothelioma

Q: What Is the Difference Between Sarcomatoid and Epithelioid Mesothelioma?

A: Sarcomatoid mesothelioma is a subtype that primarily affects the supportive tissue of internal organs. Epithelioid mesothelioma, on the other hand, affects the lining of internal organs and is the most common subtype, accounting for around 60-70% of all mesothelioma cases.

Q: Can Sarcomatoid Mesothelioma Spread to Other Parts of the Body?

A: Yes, sarcomatoid mesothelioma can spread to other parts of the body, particularly the lymph nodes and other organs. This is why early detection and treatment are crucial in managing the disease.

Q: Is Sarcomatoid Mesothelioma More Common in Men or Women?

A: Sarcomatoid mesothelioma predominantly affects men, particularly those who have worked in jobs with high levels of asbestos exposure. However, women can also develop the disease if they have been exposed to asbestos.

Q: Can Sarcomatoid Mesothelioma Be Prevented?

A: Yes, there are several measures you can take to reduce your risk of developing sarcomatoid mesothelioma, including avoiding exposure to asbestos, using protective equipment when working in high-risk industries, and following proper safety protocols when handling asbestos-containing materials.

Q: Is There a Genetic Component to Sarcomatoid Mesothelioma?

A: Although sarcomatoid mesothelioma is predominantly caused by asbestos exposure, recent studies suggest that certain genetic mutations may also play a role in the development of the disease.

Q: Can Sarcomatoid Mesothelioma Be Treated with Alternative Therapies?

A: While alternative therapies such as acupuncture, herbal supplements, and dietary changes may help manage symptoms and improve quality of life, there is currently no evidence that they can cure or slow the progression of sarcomatoid mesothelioma.

Q: Are There Support Groups for People with Sarcomatoid Mesothelioma?

A: Yes, there are several support groups and advocacy organizations dedicated to providing information, resources, and emotional support to people affected by sarcomatoid mesothelioma and their families.

Q: What Should I Do If I Have Been Diagnosed with Sarcomatoid Mesothelioma?

A: If you have been diagnosed with sarcomatoid mesothelioma, it is important to seek medical treatment as soon as possible. You may also want to consider seeking legal advice to explore your options for compensation and financial assistance.

Q: Can Sarcomatoid Mesothelioma Be Misdiagnosed?

A: Yes, sarcomatoid mesothelioma is often misdiagnosed, as its symptoms are similar to other less severe conditions. It is crucial to seek medical attention from a specialist who is experienced in diagnosing and treating mesothelioma.

Q: How Does Asbestos Exposure Cause Sarcomatoid Mesothelioma?

A: When asbestos fibers are inhaled or ingested, they can penetrate the tissues of the internal organs, causing inflammation, scarring, and eventually, cancerous tumors to form. The exact mechanism by which asbestos causes mesothelioma is not fully understood, but it is believed to involve changes in the DNA of the affected cells.

Q: Can Sarcomatoid Mesothelioma Be Treated with Immunotherapy?

A: Immunotherapy – a type of treatment that uses the body’s immune system to target cancer cells – is still being studied as a potential treatment option for sarcomatoid mesothelioma. Results so far have been mixed, and more research is needed to determine its effectiveness.

Q: Can I File a Lawsuit If I Have Been Diagnosed with Sarcomatoid Mesothelioma?

A: Yes, if you have been diagnosed with sarcomatoid mesothelioma as a result of asbestos exposure, you may be able to file a lawsuit against the company or companies responsible for the exposure. An experienced mesothelioma attorney can help you navigate the legal process and seek compensation for your medical expenses, lost wages, and other damages.

Q: Is Sarcomatoid Mesothelioma More Aggressive Than Other Types of Mesothelioma?

A: Yes, sarcomatoid mesothelioma is generally considered the most aggressive subtype of mesothelioma and is associated with a poorer prognosis than epithelioid or biphasic mesothelioma.

Q: Are There Clinical Trials Available for Sarcomatoid Mesothelioma?

A: Yes, there are several ongoing clinical trials and research studies dedicated to developing new treatments and improving outcomes for people with sarcomatoid mesothelioma. Speak to your doctor or a mesothelioma specialist to learn more about potential clinical trial opportunities.


Sarcomatoid mesothelioma is a rare and aggressive cancer that requires prompt diagnosis and treatment. While there is no known cure for the disease, there are several treatment options available to manage symptoms and improve quality of life. If you or a loved one has been diagnosed with sarcomatoid mesothelioma, we encourage you to seek medical and legal advice as soon as possible. With the right support and resources, you can take steps toward a brighter future.

Thank you for reading our article about sarcomatoid mesothelioma. We hope that you found it informative and helpful. Please feel free to share this article with others who may benefit from the information.

Closing Disclaimer

The information contained in this article is intended for educational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.