Understanding Pleural Mesothelioma: A Comprehensive Guide

Greetings to our esteemed readers. In recent times, there has been growing concern about pleural mesothelioma and its impact on human lives. Therefore, we have prepared this journal article to provide you with a comprehensive understanding of what pleural mesothelioma is, its causes, symptoms, diagnosis, treatment, and prevention. This article is designed to educate, inform, and stir up public awareness about pleural mesothelioma. We hope that you find this article informative and helpful.


Pleural mesothelioma is an aggressive and rare type of cancer that affects the lining of the lungs, known as the pleura. Mesothelioma is caused by exposure to asbestos fibers, which are a type of mineral found in products like insulation, roofing, and cement. Asbestos fibers are microscopic and, when inhaled, can lodge themselves in the pleura, causing chronic inflammation and scarring. Over time, this can lead to genetic mutations and eventually, cancerous growths.

More specifically, pleural mesothelioma accounts for around 75% of all mesothelioma cases, making it the most common type. Symptoms can take up to fifty years to develop, and the disease is often diagnosed late in its progression, making it difficult to treat. The prognosis for pleural mesothelioma is typically poor, with most patients having a life expectancy of fewer than two years. However, advances in treatment options and early detection methods have been promising in recent years.

In the following paragraphs, we will provide a detailed explanation of what pleural mesothelioma is, its types, causes, symptoms, diagnosis, treatment, and prevention. We will also address some frequently asked questions about pleural mesothelioma.

What is Pleural Mesothelioma?


Pleural mesothelioma is a type of cancer that affects the lining of the lungs known as the pleura. The pleura is a thin layer of tissue that covers the lungs and lines the inside of the chest cavity. It is made of two layers, the visceral pleura, and the parietal pleura, which are separated by a thin layer of fluid. The inner layer, the visceral pleura, covers the lungs, while the outer layer, the parietal pleura, lines the inside of the chest cavity.


As mentioned earlier, pleural mesothelioma is primarily caused by exposure to asbestos fibers. Asbestos was commonly used in construction and manufacturing industries, and it was prevalent during the 20th century. People who have worked in these industries or lived in buildings that contain asbestos are at risk of developing pleural mesothelioma. The inhalation of asbestos fibers causes chronic inflammation and scarring in the pleura, which leads to genetic mutations and eventually the formation of cancerous growths.


The symptoms of pleural mesothelioma can take between twenty to fifty years after exposure to asbestos to develop. Pleural mesothelioma symptoms include:

Symptoms Description
Chest pain Pain in the chest wall or under the ribcage
Shortness of breath Breathing difficulty, especially during exercise or physical activity
Fatigue Feeling of exhaustion, even after proper rest
Coughing Persistent dry cough or coughing up blood
Weight loss Unintentional weight loss
Fever Low-grade fever or sweating at night
Difficulty swallowing Feeling of obstruction while swallowing food or liquids


Diagnosing pleural mesothelioma can be challenging since the symptoms are often similar to other respiratory conditions like tuberculosis, asthma, and pneumonia. However, the following tests can help diagnose pleural mesothelioma:

Imaging Tests

X-rays, CT scans, MRI scans, and PET scans can detect any abnormalities in the lungs and chest wall. These tests can reveal if there are any masses or nodules in the pleura, suggesting cancerous growths.


A tissue sample is taken from the pleura and examined under a microscope. This test is considered the most definitive way of diagnosing pleural mesothelioma.


Depending on the stage and severity of pleural mesothelioma, some treatment options are as follows:


Surgery can be used to remove the cancerous growth, as well as the affected pleura and nearby lymph nodes. Surgery can provide the best chance for survival, but it is usually only performed on early-stage tumors.


Chemotherapy uses drugs to kill cancer cells throughout the body. It is often used in combination with surgery, and it involves a series of intravenous injections or oral medication.

Radiation therapy:

Radiation therapy is the use of high-energy beams to kill cancer cells. It can be used as a standalone treatment or in combination with other treatments.


Asbestos is banned in more than sixty countries worldwide, including the United States. If you work or live in an area where asbestos is present, take the necessary precautions to prevent exposure. Wear protective equipment like respiratory masks and clothing that can prevent asbestos fibers from attaching to the skin and clothing. Proper ventilation and asbestos removal or encapsulation procedures should also be followed.

FAQs About Pleural Mesothelioma

1. Can Pleural Mesothelioma Be Cured?

Pleural mesothelioma can’t be cured, but treatment can help manage the symptoms and prolong life.

2. How Long Can You Live With Pleural Mesothelioma?

The life expectancy of a person with pleural mesothelioma is usually between twelve to twenty-one months. However, early detection and treatment can prolong life expectancy.

3. How Is Pleural Mesothelioma Different From Lung Cancer?

Pleural mesothelioma affects the lining of the lungs, while lung cancer affects the lung tissue itself. The causes and symptoms of both diseases are different as well.

4. Can Secondhand Exposure to Asbestos Cause Pleural Mesothelioma?

Yes, secondhand exposure can cause pleural mesothelioma. For instance, if someone who is exposed to asbestos fibers goes home and hugs their family members, those family members can also inhale the fibers and develop pleural mesothelioma.

5. What Are the Stages of Pleural Mesothelioma?

Pleural mesothelioma is divided into four stages: stage 1 (localized), stage 2 (advanced but still operable), stage 3 (advanced but inoperable), and stage 4 (metastatic and incurable)

6. Can Smoking Increase the Risk of Developing Pleural Mesothelioma?

No, smoking does not increase the risk of developing pleural mesothelioma. However, smoking can exacerbate the symptoms of the disease.

7. Can Diet Help Prevent Pleural Mesothelioma?

There is no specific diet that can prevent pleural mesothelioma. However, a healthy and balanced diet can help improve overall health and reduce the risk of developing other health conditions.

8. How Long Does It Take for Asbestos Exposure to Cause Pleural Mesothelioma?

It can take between twenty to fifty years after asbestos exposure for pleural mesothelioma symptoms to develop.

9. Can Pleural Mesothelioma Be Detected Early?

Yes, pleural mesothelioma can be detected early through routine imaging tests and screenings. Early detection can help improve treatment outcomes.

10. Can Pleural Mesothelioma Spread to Other Parts of the Body?

Yes, if left untreated, pleural mesothelioma can spread to other parts of the body like the chest wall, diaphragm, and lymph nodes.

11. Can Exercise Help Manage Pleural Mesothelioma Symptoms?

Yes, exercise can help manage pleural mesothelioma symptoms like fatigue and shortness of breath. It can also improve quality of life.

12. Can Support Groups Help People With Pleural Mesothelioma?

Yes, joining a support group can help people with pleural mesothelioma connect with others who are going through similar experiences. It can provide support, encouragement, and helpful information.

13. Are Clinical Trials Available for Pleural Mesothelioma?

Yes, there are many clinical trials available for pleural mesothelioma. Participating in a clinical trial can provide access to new treatment options and help improve treatment outcomes.


We hope that this article has provided you with a detailed understanding of what pleural mesothelioma is, its causes, symptoms, diagnosis, treatment, and prevention. We encourage you to take necessary precautions to prevent exposure to asbestos and to seek medical attention if you experience any of the symptoms mentioned earlier. Early detection and treatment can improve treatment outcomes and prolong life expectancy. Lastly, we hope that this article has raised public awareness about pleural mesothelioma and the importance of supporting those who are affected by it.

Closing Disclaimer

The information provided in this article is for educational and informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. None of the content should be viewed as an endorsement, recommendation, or promotion of any particular treatment, product, or diagnostic test. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.